Reactive species
Human,Mouse,Rat
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 75 kDa; Observed MW: 68 kDa
Immunogen
synthesized peptide derived from human TGFBI
Specificity
Affinity Chromatography
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Background
TGFBI is a RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
