Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
U6 snRNA-associated Sm-like protein LSm5
Immunogen
Synthesized peptide derived from human LSM5
Specificity
This antibody detects endogenous levels of LSM5 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, and 0.2089% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
’-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) . The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA .
