Antibody type
Monoclonal antibodies
Immunogen
synthesized peptide derived from Human CD303 Purification Affinity Purified Conjugation FITC Modification Unmodified Form Liquid.
Constitute
Liquid in PBS with 0.05% Proclin300, 1% BSA
Stockpile
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles
Background
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.
