Reactive species
Human, Mouse
Antibody type
Polyclonal Antibody
Protein name
Protein MCM10 homolog (HsMCM10)
Immunogen
Synthesized peptide derived from human N-ternal MCM10
Specificity
This antibody detects endogenous levels of MCM10 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IHC 1:50-200
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Protein MCM10 homolog (HsMCM10)
Function
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 .
