Reactive species
Human;Mouse
Applications
WB;ELISA;IHC
Antibody type
Polyclonal Antibody
Protein name
ITGA5 (heavy chain, Cleaved-Arg894)
Immunogen
Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
Specificity
This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Integrin alpha-5 (CD49 antigen-like family member E;Fibronectin receptor subunit alpha;Integrin alpha-F;VLA-5;CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Background
function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
Function
cell motion, cell-substrate junction assembly, cell adhesion, heterophilic cell adhesion, leukocyte adhesion, cell surface receptor linked signal transduction, integrin-mediated signaling pathway, behavior, learning or memory, memory,response to wounding, cell-cell adhesion, cell migration, biological adhesion, cell adhesion mediated by integrin, cell-cell adhesion mediated by integrin, cell junction assembly, cell junction organization, wound healing, spreading of epidermal cells, wound healing, cell motility, neurological system process, cognition, localization of cell,
