Reactive species
Human;Rat
Antibody type
Polyclonal Antibody
Protein name
Potassium channel subfamily K member 1
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336
Specificity
TWIK-1 Polyclonal Antibody detects endogenous levels of TWIK-1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
KCNK1; HOHO1; KCNO1; TWIK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1
Background
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
Function
function:Weakly inward rectifying potassium channel.,miscellaneous:Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney.,
