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CLIC3 Polyclonal Antibody

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CLIC3 Polyclonal Antibody

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Product code: YP-Ab-16404

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human;Rat;Mouse;

Applications

WB;ELISA

Antibody type

Polyclonal Antibody

Gene Name

CLIC3

Protein name

Chloride intracellular channel protein 3

Dalton（DA）

27kD

Immunogen

The antiserum was produced against synthesized peptide derived from human CLIC3. AA range:21-70

Specificity

CLIC3 Polyclonal Antibody detects endogenous levels of CLIC3 protein.

Constitute

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source

Polyclonal, Rabbit,IgG

Dilution rate

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purification process

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Stockpile

-20°C/1 year

Other name

CLIC3; Chloride intracellular channel protein 3

Background

chloride intracellular channel 3(CLIC3) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008],

Function

domain:Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.,function:Can insert into membranes and form chloride ion channels. May participate in cellular growth control.,similarity:Belongs to the chloride channel CLIC family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subcellular location:Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.,subunit:Associated with the C-terminal of ERK7.,tissue specificity:Detected in placenta (at protein level). Widely expressed. High expression is fou

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IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

CLIC3 Polyclonal Antibody

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CLIC3 Polyclonal Antibody

Product introduction

Product Details

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Citation

Background information

FAQ

Experimental scheme

IP

WB

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