Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
ATP synthase subunit s mitochondrial
Immunogen
The antiserum was produced against synthesized peptide derived from human ATP5S. AA range:21-70
Specificity
ATP5S Polyclonal Antibody detects endogenous levels of ATP5S protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
ATP5S; ATPW; ATP synthase subunit s; mitochondrial; ATP synthase-coupling factor B; FB; Mitochondrial ATP synthase regulatory component factor B
Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Function
caution:It is uncertain whether Met-1 or Met-16 is the initiator.,function:Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase.,similarity:Belongs to the ATP synthase subunit s family.,subunit:Monomer. Associates with ATP synthase.,