Reactive species
Human;Mouse;Rat
Applications
WB;ELISA;IHC CoIP
Antibody type
Polyclonal Antibody
Protein name
Ras-related GTP-binding protein C
Immunogen
The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351
Specificity
Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; IP 1:50-200 ELISA 2000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
RRAGC; Ras-related GTP-binding protein C; Rag C; RagC; GTPase-interacting protein 2; TIB929
Background
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
Function
function:Has guanine nucleotide-binding activity but weak intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,