Reactive species
Human;Mouse
Applications
WB;IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Rab11 family-interacting protein 4
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB11FIP4. AA range:452-501
Specificity
Rab11-FIP4 Polyclonal Antibody detects endogenous levels of Rab11-FIP4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
RAB11FIP4; ARFO2; KIAA1821; Rab11 family-interacting protein 4; FIP4-Rab11; Rab11-FIP4; Arfophilin-2
Background
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008],
Function
function:A Rab11 effector protein acting in the endosomal trafficking.,similarity:Contains 1 EF-hand domain.,subcellular location:Colocalizes with RAB11A in the endocytic recycling compartment (ERC).,subunit:Homooligomer. Forms an heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with RAB11A that has been activated by GTP binding.,
