Home / Products / Polyclonal antibody /

Rab 3 GAP p150 Polyclonal Antibody

Product navigation

Rab 3 GAP p150 Polyclonal Antibody

Citation (0) Contact

Product code: YP-Ab-16195

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human;Mouse;Rat;Monkey

Applications

WB;IHC;IF;ELISA

Antibody type

Polyclonal Antibody

Gene Name

RAB3GAP2

Protein name

Rab3 GTPase-activating protein non-catalytic subunit

Dalton（DA）

156kD

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB3GAP2. AA range:417-466

Specificity

Rab 3 GAP p150 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p150 protein.

Constitute

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source

Polyclonal, Rabbit,IgG

Dilution rate

WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200

Purification process

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Stockpile

-20°C/1 year

Other name

RAB3GAP2; KIAA0839; Rab3 GTPase-activating protein non-catalytic subunit; RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit

Background

The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009],

Function

disease:Defects in RAB3GAP2 are the cause of Martsolf syndrome [MIM:212720]. Martsolf syndrome is characterized by congenital cataracts, mental retardation, and hypogonadism. Inheritance is autosomal recessive.,function:Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.,similarity:Belongs to the Rab3-GAP regulatory subunit family.,subcellular location:In neurons, it is enriched in the synaptic soluble fracti

Open

Product Details

Customer data and reviews (0)

Fold content

Citation

Fold content

Background information

FAQ

Fold content

Experimental scheme

Fold content

IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

Rab 3 GAP p150 Polyclonal Antibody

Product navigation

Rab 3 GAP p150 Polyclonal Antibody

Product introduction

Product Details

Customer data and reviews (0)

Citation

Background information

FAQ

Experimental scheme

IP

WB

Primary antibodies

Secondary antibodies

Elisa Kit

Biochemical kit

Recombinant protein

Antibody customization service

ELISA service

Protein service

Biochemical testing services

Literature search

Antibody application technology resources

ELISA application technology resources

Research strategies and research tools

Product literature citation

About Us

Recruit

News

Contact

Technical FAQ