Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Rho guanine nucleotide exchange factor 5
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF5. AA range:191-240
Specificity
Oncogene TIM Polyclonal Antibody detects endogenous levels of Oncogene TIM protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
ARHGEF5; TIM; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM
Background
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Mainly expressed in kidney, liver, pancreas, lung and placenta.,
