Antibody type
Monoclonal antibodies
Immunogen
Purified recombinant human Rab2 protein fragments expressed in E.coli.
Specificity
This antibody detects endogenous levels of Rab2 and does not cross-react with related proteins.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
wb 1:1000 icc 1:200
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Other name
9330148M11Rik;C80220;GTP binding protein;LHX;OTTMUSP00000004796;RAB2;RAB2 member RAS oncogene family;RAB2A;RAB2A, member RAS oncogene family;RAB2A_HUMAN;Ras related protein Rab 2A;RAS-associated protein RAB2;Ras-related protein Rab-2A;RP23-183L6.1;Small GTP binding protein RAB2A.
Background
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
function:Required for protein transport from the endoplasmic reticulum to the Golgi complex.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Interacts with PRKCI.,
