Reactive species
Human;Mouse;Rat,Sheep
Applications
WB;IHC;IF;ELISA
Protein name
Fibroblast growth factor 18
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF18. AA range:158-207
Specificity
FGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
FGF18; Fibroblast growth factor 18; FGF-18; zFGF5
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008],
Function
function:Stimulates hepatic and intestinal proliferation.,similarity:Belongs to the heparin-binding growth factors family.,
