Reactive species
                            
                                Human;Mouse                            
                         
                                                
                            Applications
                            
                                IHC;IF;ELISA                            
                         
                                                
                                                
                                                
                            Protein name
                            
                                Tumor necrosis factor alpha-induced protein 2                            
                         
                                                
                                                
                            Immunogen
                            
                                The antiserum was produced against synthesized peptide derived from human TNAP2. AA range:131-180                            
                         
                                                
                            Specificity
                            
                                TNFα-IP 2 Polyclonal Antibody detects endogenous levels of TNFα-IP 2 protein.                            
                         
                                                
                            Constitute
                            
                                Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.                            
                         
                                                
                            Source
                            
                                Polyclonal, Rabbit,IgG                            
                         
                                                
                            Dilution rate
                            
                                Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.                            
                         
                                                
                            Purification process
                            
                                The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.                            
                         
                                                
                                                
                                                
                            Other name
                            
                                TNFAIP2; Tumor necrosis factor alpha-induced protein 2; TNF alpha-induced protein 2; Primary response gene B94 protein                            
                         
                                                
                            Background
                            
                                This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008],                            
                         
                                                
                            Function
                            
                                developmental stage:Differentially expressed in development and capillary tube-like formation in vitro.,function:May play a role as a mediator of inflammation and angiogenesis.,induction:By TNF-alpha and other proinflammatory factors.,similarity:Belongs to the SEC6 family.,