Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
L-amino-acid oxidase
Immunogen
Synthesized peptide derived from the N-terminal region of human IL-4I1.
Specificity
IL-4I1 Polyclonal Antibody detects endogenous levels of IL-4I1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
IL4I1; FIG1; L-amino-acid oxidase; LAAO; LAO; Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1
Background
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
Function
catalytic activity:An L-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).,cofactor:FAD.,function:Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation.,induction:By interleukin-4.,similarity:Belongs to the flavin monoamine oxidase family. FIG1 subfamily.,tissue specificity:Primarily found in immune tissues (isoform 1).,
