Reactive species
Human;Mouse
Applications
WB;IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Iroquois-class homeodomain protein IRX-1
Immunogen
The antiserum was produced against synthesized peptide derived from human IRX1. AA range:221-270
Specificity
IRX1 Polyclonal Antibody detects endogenous levels of IRX1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
IRX1; IRXA1; Iroquois-class homeodomain protein IRX-1; Homeodomain protein IRXA1; Iroquois homeobox protein 1
Background
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011],
Function
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
