Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Homeobox protein Hox-B4
Immunogen
The antiserum was produced against synthesized peptide derived from human HoxB4. AA range:86-135
Specificity
HoxB4 Polyclonal Antibody detects endogenous levels of HoxB4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
HOXB4; HOX2F; Homeobox protein Hox-B4; Homeobox protein Hox-2.6; Homeobox protein Hox-2F
Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008],
Function
developmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family. Deformed subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
