Reactive species
Human; Predict react with Mouse, Rat
Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human TRAP
Specificity
The antibody can specifically recognize human TRAP protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.97% sodium azide.
Source
Mouse, Monoclonal/IgG1, Kappa
Dilution rate
IHC-p 1:100-500, IF 1:100-500
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Other name
Tartrate-resistant acid phosphatase type 5 (TR-AP;EC 3.1.3.2;Tartrate-resistant acid ATPase;TrATPase;Type 5 acid phosphatase)
Background
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008],
Function
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 2 iron ions per subunit.,disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias).,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.,subunit:Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).,
