Reactive species
Human; Predict react with Mouse, Rat
Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human PSAP
Specificity
The antibody can specifically recognize human PSAP protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.106% sodium azide.
Source
Mouse, Monoclonal/IgG2b, Kappa
Dilution rate
IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Other name
Prostatic acid phosphatase (PAP;EC 3.1.3.2;5'-nucleotidase;5'-NT;EC 3.1.3.5;Ecto-5'-nucleotidase;Thiamine monophosphatase;TMPase) [Cleaved into: PAPf39]
Background
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008],
Function
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,similarity:Belongs to the histidine acid phosphatase family.,subcellular location:Predominantly localized in the plasma membrane but also detected in intracellular vesicles.,subunit:Homodimer.,
