Reactive species
Human; Predict react with Mouse, Rat
Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human MAGE-C1
Specificity
The antibody can specifically recognize human MAGE-C1 protein. In western blotting of K562 cell lysate, the antibody can label a 190KDa band corresponding to MAGE-C1.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% sodium azide.
Source
Mouse, Monoclonal/IgG1, Kappa
Dilution rate
IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Other name
Melanoma-associated antigen C1 (Cancer/testis antigen 7.1;CT7.1;MAGE-C1 antigen)
Background
This gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 MAGE domain.,tissue specificity:Expressed in testis and in tumors of a wide variety of histologic types.,
