Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human Calponin-1
Specificity
The antibody can specifically recognize human and mouse calponin-1 protein. In western blotting of Hela, LnCap and mouse muscle lysates, the antibody can label a 34KDa band corresponding to calponin-
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% sodium azide.
Source
Mouse, Monoclonal/IgG2a, kappa
Dilution rate
IHC-p 1:100-500, WB 1:200-1000, IF 1:100-500
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Other name
Calponin-1 (Basic calponin;Calponin H1, smooth muscle)
Function
function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
