Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human Calponin-1
Specificity
This antibody detects endogenous levels of Calponin-1 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC-p 1:5-1:10. IF 1:50-200
Purification process
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
Other name
Calponin-1 (Basic calponin;Calponin H1, smooth muscle)
Function
function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
