Antibody type
Monoclonal antibodies
Protein name
Cytokeratin 19 (CK19)
Immunogen
Synthesized peptide derived from human Cytokeratin 19 (CK19)
Specificity
This antibody detects endogenous levels of Cytokeratin 19 (CK19) at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC-p 1:100-1:200. IF 1:50-200
Purification process
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
Other name
Keratin, type I cytoskeletal 19 (Cytokeratin-19;CK-19;Keratin-19;K19)
Function
developmental stage:Present in hair follicles at all stages of development.,domain:This keratin differs from all other IF proteins in lacking the C-terminal tail domain.,function:Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein.,tissue specificity:Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestin
