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EphA4 Monoclonal Antibody

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EphA4 Monoclonal Antibody

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Product code: YP-Ab-12908

Promotional price: $ 255

100UL 53UL 10UL

Product introduction

Reactive species

Human

Applications

WB;ELISA

Antibody type

Monoclonal antibodies

Gene Name

EPHA4

Protein name

Ephrin type-A receptor 4

Dalton（DA）

Immunogen

Purified recombinant fragment of EphA4 (aa777-986) expressed in E. Coli.

Specificity

EphA4 Monoclonal Antibody detects endogenous levels of EphA4 protein.

Constitute

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Source

Monoclonal, Mouse

Dilution rate

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification process

Affinity purification

Concentration

Stockpile

-20°C/1 year

Other name

EPHA4; HEK8; SEK; TYRO1; Ephrin type-A receptor 4; EPH-like kinase 8; EK8; hEK8; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase receptor SEK

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],

Function

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The protein kinase domain mediates interaction with NGEF/ephexin-1.,function:Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,subunit:Interacts with the src family kinase, p59-Fyn, through the major phosphorylation site at position Tyr-602. Interacts with NGEF/ephexin-1.,tissue specificity:Ubiquitous.

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IP

常规Immunoprecipitation（免疫沉淀 IP）实验操作步骤

WB

蛋白免疫印迹（WB) 实验步骤

EphA4 Monoclonal Antibody

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EphA4 Monoclonal Antibody

Product introduction

Product Details

Customer data and reviews (0)

Citation

Background information

FAQ

Experimental scheme

IP

WB

Primary antibodies

Secondary antibodies

Elisa Kit

Biochemical kit

Recombinant protein

Antibody customization service

ELISA service

Protein service

Biochemical testing services

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