Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
KRTAP8-1 KAP8.1 KRTAP8.1
Immunogen
Synthesized peptide derived from human KRA81 AA range: 13-63
Specificity
This antibody detects endogenous levels of KRA81 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC-p 1:50-200. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 8 family.,subunit:Interacts with hair keratins.,tissue specificity:Is essentially restricted to only one vertical half of the hair forming compartment and in beard hairs is absent from the central medulla.,