Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
SLIT and NTRK-like protein 4
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Specificity
SLIK4 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
Function
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 18 LRR (leucine-rich) repeats.,tissue specificity:Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, gliobastomas and primitive neuroectodermal tumors.,
