Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Transcription factor SOX-4
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SOX4 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],
Function
function:Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Interacts with UBE2I.,tissue specificity:Testis, brain, and heart.,
