Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
PDCD5 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],
Function
developmental stage:Expression in fetal tissues is significantly lower than in adult tissues.,function:May function in the process of apoptosis.,induction:Activated in cells undergoing apoptosis.,similarity:Belongs to the PDCD5 family.,tissue specificity:Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.,
