Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
IGFBPL1 IGFBPRP4
Protein name
Insulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
IBPL1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,
Function
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,
