Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
BTF3 NACB OK/SW-cl.8
Protein name
Transcription factor BTF3 (RNA polymerase B transcription factor 3)
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Specificity
BTF3 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008],
Function
function:General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NAC-beta family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
