Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Sjoegren syndrome/scleroderma autoantigen 1 (Autoantigen p27)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SSA27 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008],
Function
function:Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,
