Reactive species
Human;Rat;Mouse
Antibody type
Polyclonal Antibody
Protein name
Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
BOP1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,
Function
function:Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.,induction:By MYC.,similarity:Belongs to the WD repeat BOP1/ERB1 family.,similarity:Contains 7 WD repeats.,subunit:Component of the PeBoW complex, composed of bop1, pes1 and wdr12. Within the PeBoW complex bop1 interacts directly with pes1 and wdr12. The PeBoW complex also associates with the 66S pre-ribosome.,