Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
NSUN5 WBSCR20 WBSCR20A
Protein name
Putative methyltransferase NSUN5 (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein)
Immunogen
Synthesized peptide derived from human protein . at AA range: 320-400
Specificity
NSUN5 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],
Function
function:May have S-adenosyl-L-methionine-dependent methyl-transferase activity .,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the methyltransferase superfamily. RsmB/NOP family.,tissue specificity:Ubiquitous. Detected in placenta, heart and skeletal muscle.,
