Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
PRDM10 KIAA1231 PFM7 TRIS
Protein name
PR domain zinc finger protein 10 (PR domain-containing protein 10) (Tristanin)
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Specificity
PRD10 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Function
domain:The SET domain is degenerated, suggesting that it has lost mehtyltransferase activity.,function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 SET domain.,similarity:Contains 10 C2H2-type zinc fingers.,
