Reactive species
Human;Rat;Mouse
Antibody type
Polyclonal Antibody
Protein name
Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Specificity
NUFP1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012],
Function
function:Binds RNA.,similarity:Contains 1 C2H2-type zinc finger.,subcellular location:Distributed in the nucleus in a dot-like pattern.,subunit:Interacts with FMR1.,tissue specificity:Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.,
