Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Nidogen-2 (NID-2) (Osteonidogen)
Immunogen
Synthesized peptide derived from human protein . at AA range: 700-780
Specificity
NID2 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
nidogen 2(NID2) Homo sapiens This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010],
Function
function:Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.,PTM:Highly N- and O-glycosylated.,similarity:Contains 1 NIDO domain.,similarity:Contains 1 nidogen G2 beta-barrel domain.,similarity:Contains 2 thyroglobulin type-1 domains.,similarity:Contains 5 EGF-like domains.,similarity:Contains 5 LDL-receptor class B repeats.,subunit:Interacts with LAMA2 (By similarity). Interacts with COL13A1.,tissue specificity:Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.,
