Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
NRXN3 C14orf60 KIAA0743
Protein name
Neurexin-3-alpha (Neurexin III-alpha)
Immunogen
Synthesized peptide derived from human protein . at AA range: 480-560
Specificity
NRX3A Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
alternative products:A number of isoforms, alpha-type (AC Q9Y4C0) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,alternative products:A number of isoforms, alpha-type (shown here) and beta-type (AC Q9HDB5), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus. Additional isoforms produced by alternative splicing seem to exist,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subunit:The cytoplasmic C-terminal region binds to CASK (By similarity). Binds to neuroligins NLGN1, NLGN2 and NLGN3.,subunit:The laminin G-like domain 2 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. The cytoplasmic C-terminal region binds to CASK.,tissue specificity:Predominantly expressed in brain.,
Function
alternative products:A number of isoforms, alpha-type (AC Q9Y4C0) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,alternative products:A number of isoforms, alpha-type (shown here) and beta-type (AC Q9HDB5), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus. Additional isoforms produced by alternative splicing seem to exist,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subun
