Reactive species
Human;Rat;Mouse
Applications
WB; IF;ELISA
Antibody type
Polyclonal Antibody
Gene Name
CDHR5 MUCDHL MUPCDH UNQ2781/PRO7168
Protein name
Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein)
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Specificity
CDHR5 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
cadherin related family member 5(CDHR5) Homo sapiens This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010],
Function
function:Acts as a calcium-dependent cell adhesion protein.,PTM:N- and O-glycosylated.,similarity:Contains 4 cadherin domains.,tissue specificity:Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver.,
