Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Folate receptor gamma (FR-gamma) (Folate receptor 3)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
FOLR3 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
Function
function:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate.,PTM:Eight disulfide bonds are present.,similarity:Belongs to the folate receptor family.,tissue specificity:Spleen, thymus, bone marrow, ovarian carcinoma, and uterine carcinoma.,
