Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Gene Name
HSD17B2 EDH17B2
Protein name
Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxys
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
DHB2 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Function
catalytic activity:Estradiol-17-beta + NAD(P)(+) = estrone + NAD(P)H.,catalytic activity:Testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH.,function:Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
