Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RPOM Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.,similarity:Belongs to the phage and mitochondrial RNA polymerase family.,subunit:Interacts with TFB1M and TFB2M, leading to the stimulation of transcription.,
