Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
DPOA2 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
Function
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
