Background
This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Function
cell cycle checkpoint, DNA damage checkpoint, M phase of mitotic cell cycle, microtubule cytoskeleton organization,mitotic cell cycle, M phase, nuclear division, response to DNA damage stimulus, cytoskeleton organization, microtubule-based process, cell cycle, spindle organization, mitosis, intracellular signaling cascade, cell cycle process, cell cycle phase, DNA integrity checkpoint, cellular response to stress, DNA damage response, signal transduction, organelle fission, spindle assembly, cell division, regulation of cell cycle,
