Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CBPB1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Preferential release of a C-terminal lysine or arginine amino acid.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Pancreas.,
