Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Aquaporin-10 (AQP-10) (Aquaglyceroporin-10) (Small intestine aquaporin)
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Specificity
AQP10 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq, Jul 2008],
Function
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water channel. Not permeable to urea and glycerol. May contribute to water transport in the upper portion of small intestine.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.,
