Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
CRLF3 CREME9 CYTOR4 P48
Protein name
Cytokine receptor-like factor 3 (Cytokine receptor-like molecule 9) (CREME-9) (Cytokine receptor-related protein 4) (Type I cytokine receptor-like factor p48)
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Specificity
CRLF3 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012],
Function
similarity:Belongs to the cytokine receptor-like factor 3 family.,similarity:Contains 1 fibronectin type-III domain.,tissue specificity:Expressed in skin and squamous cell carcinoma (SCC) and in lesion actinic keratosis (AK).,
