Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)
Immunogen
Synthesized peptide derived from human protein . at AA range: 260-340
Specificity
MTF1 Polyclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008],
Function
function:Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).,similarity:Contains 6 C2H2-type zinc fingers.,
