Reactive species
Human virus
Antibody type
Monoclonal antibodies
Gene Name
SARS-COV-2 Spike Protein
Protein name
SARS-COV-2 Spike Protein
Immunogen
Synthesized peptide derived from SARS-COV-2 Spike Protein
Specificity
This antibody detects endogenous levels of SARS-COV-2 Spike Protein
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.22% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
