Reactive species
Human:K336/304;Mouse:K336/304;Rat:K336/305
Antibody type
Polyclonal Antibody
Protein name
GATA binding protein 2/GATA binding protein 3
Immunogen
Synthesized acetyl-peptide from human protein at AA range: 320-390
Specificity
This antibody detects endogenous levels of GATA-2/3 at Human:K336/304;Mouse:K336/304;Rat:K336/305, It doesn't reacte with total protein.
Constitute
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1:500-10000 ELISA: 1:10000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],
Function
function:Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.,sequence caution:Several sequencing errors.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Endothelial cells.,
